Professors Paul Stasiewicz and Clara Bradizza, Adjunct Instructor Braden Linn, and their colleagues publish article, "The Identification of Pretreatment Trajectories of Alcohol Use and Their Relationship to Treatment Outcome in Men and Women With Alcohol Use Disorder"

Published February 10, 2020

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Paul Stasiewicz

Paul Stasiewicz.

Clara Bradizza

Clara Bradizza.

Braden Linn

Braden Linn.

Congratulations to Professor Paul Stasiewicz, Professor Clara Bradizza, Adjunct Instructor Braden Linn, and their colleagues on the publication of their article "The Identification of Pretreatment Trajectories of Alcohol Use and Their Relationship to Treatment Outcome in Men and Women With Alcohol Use Disorder," in Alcoholism: Clinical and Experimental Research.

Stasiewicz, P. R., Bradizza, C. M., Ruszczyk, M. U., Lucke, J. F., Zhao, J., Linn, B., Slosman, K. S, & Dermen, K. H. (2019). The identification of pretreatment trajectories of alcohol use to treatment outcome in men and women with alcohol use disorder. Alcoholism: Clinical and Experimental Research.

Abstract

Background

Few studies have focused on behavioral changes that occur prior to entering treatment for an alcohol use disorder (AUD). In 2 studies (Psychol Addict Behav, 27, 2013, 1159; J Stud Alcohol, 66, 2005, 369), pretreatment reductions in alcohol use were associated with better treatment outcomes. Identifying patterns of pretreatment change has the potential to inform clinical decision making.

Methods

This study sought to identify pretreatment change trajectories in individuals seeking outpatient treatment for AUD (N = 205) using finite mixture modeling based on changes in number of days abstinent per week (NDA).

Results

The analysis identified 3 pretreatment trajectory classes. Class 1 (High Abstinence—Minimal Increase; HA‐MI) (n = 64; 31.2%) reported a high level of pretreatment NDA with minimal change during an 8‐week pretreatment interval. Class 2 (Low Abstinence—Steady Increase; LA‐SI) (n = 73; 35.6%) reported a low level of pretreatment NDA followed by a steady increase beginning 2 weeks prior to the phone screen. Class 3 (Nonabstinent—Accelerated Increase; NA‐AI) (n = 68; 33.2%) reported no or very low levels of pretreatment NDA but demonstrated an increase following the phone screen. With regard to within‐treatment change, Class 1 demonstrated the least and Class 3 demonstrated the most change in NDA. From baseline to 6‐month follow‐up, Class 3 added 2.31 abstinent days per week, Class 2 added 0.69 days, and Class 1 added 0.63 days. The increase in NDA for Class 3 was significantly different from the other 2 classes; however, Class 3 reported fewer overall days abstinent at 6‐month follow‐up.

Conclusions

Study results have clinical and research implications including recommended changes to treatment protocols and research designs. Understanding the impact of pretreatment trajectories of alcohol use on within‐treatment and posttreatment outcomes may provide important information about adapting treatment to increase efficiency and effectiveness.